What Exactly Is Spravato and How Does It Work?

Spravato (esketamine) works differently than traditional antidepressants by targeting the NMDA receptors in your brain. This FDA-approved medication offers hope for the 30% of depression patients who don’t respond to conventional treatments. Before discussing side effects, it’s important to understand that Spravato is always administered under medical supervision at certified treatment centers like ours in Chatham, New Jersey.

The 5 Most Common Spravato Side Effects You May Experience

Based on clinical studies and our extensive patient experience at Spravato Treatment Centers of New Jersey, these are the side effects most patients should be prepared for:

1. Dissociation: Approximately 41% of patients experience feeling disconnected from reality or altered perceptions. This typically resolves within 1-2 hours after treatment.
2. Dizziness and Nausea: Nearly 29% of patients report feeling dizzy or nauseated during or shortly after administration. Having a light meal before treatment can help minimize these effects.
3. Blood Pressure Changes: About 17% of patients experience temporary increases in blood pressure, which is why monitoring is required during each treatment session.
4. Sedation and Drowsiness: Around 23% of patients feel extremely relaxed or sleepy, which is why you’ll need someone to drive you home after treatment.
5. Anxiety or Agitation: Some patients (13%) report temporary feelings of anxiety during the treatment experience.

Olivia’s Journey: From Treatment-Resistant Depression to Renewal

Olivia, a 45-year-old engineer from northern New Jersey, had battled treatment-resistant depression for over a decade. “I tried six different antidepressants and years of therapy with minimal improvement,” she recalls.

Today, Olivia continues maintenance Spravato treatments and reports an 80% reduction in her depression symptoms. “The temporary side effects were a small price to pay for getting my life back,” she says.

How Our Medical Team Manages Side Effects

At Spravato Treatment Centers of New Jersey, our experienced medical team led by our Medical Director has developed protocols specifically designed to minimize discomfort during treatment:

• Pre-treatment preparation guidance to reduce nausea
• Comfortable, private treatment rooms with calming environments
• Continuous monitoring by specialized healthcare professionals
• Post-treatment recovery period with personalized support
• Follow-up care to address any lingering side effects

Will Insurance Cover Spravato Despite Its Side Effects?

Many patients worry that insurance companies might deny coverage due to potential side effects. The good news is that most major insurance providers now recognize Spravato’s effectiveness for treatment-resistant depression. Visit our cost and insurance page to learn about coverage options and our assistance programs that make treatment accessible regardless of your financial situation.

Frequently Asked Questions About Spravato Side Effects

Our patients often have specific concerns about side effects before starting treatment. Here are answers to the most common questions we receive at our Chatham clinic:

How long do the dissociative effects typically last?
Most patients find that dissociation resolves within 1-2 hours after treatment. By the time you’re cleared to go home (approximately 2 hours post-treatment), these effects have typically subsided significantly.

Can I drive after receiving Spravato?
No. Due to the potential for drowsiness and dissociation, you must arrange for someone to drive you home after each treatment session. You should not operate machinery or make important decisions until the following day.

Do side effects diminish with continued treatment?
Many patients report that side effects like dissociation and dizziness become less intense as they progress through their treatment course, though individual experiences vary.