Esketamine for depression – a new option!

Esketamine is a new medication for the treatment of major depression. It is an injectable, non-opioid based medicine that has been shown to be effective in reducing depressive symptoms, even when other treatments have failed.

Esketamine is an active metabolite of ketamine, a drug that has been used for years as an anesthetic and sometimes as a street drug. Esketamine is not addictive and does not have the same abuse potential as ketamine.

The FDA approved Spravato (esketamine) in June 2019 for use in treating major depressive disorder (MDD) in adults who have failed to respond adequately to two or more antidepressants at therapeutic doses for their current episode. The approval was based on results from two clinical trials showing that Spravato improved depression symptoms within 1 week after treatment compared with placebo.

Depression can be suffocating

Spravato Treatment for Depression

Depression is a serious medical condition that affects about 1 in every 20 people. Although there are many effective medications for depression, many people do not respond adequately to the first drug they try. If you have tried antidepressants before and are still experiencing symptoms of depression, such as low mood or anxiety, it may be time to consider other treatment options.

Spravato (esketamine) is a new medication that has been approved by the FDA for the treatment of major depressive disorder (MDD). It belongs to a class of drugs called NMDA receptor antagonists, which work by blocking signals in the brain that may contribute to depression.

 

Relief is in sight, even for those who've failed other treatments

Spravato treatment centers

This medication has been studied in clinical trials as adjunctive therapy and has been found to be more effective when combined with an antidepressant than when used alone. It is important to understand, however, that it does not work for everyone – just like any other medication – so it may not be right for you if you have already tried other antidepressants without success.

Spravato has been found to be both safe and effective as an antidepressant medication; however, like any other medication it may have side effects such as nausea or vomiting which will lessen over time with continued use as your body adjusts itself to having higher levels of these chemicals circulating through its system

Author’s Bio

Dr. David Boguslavsky, MD, is a highly experienced family physician and medical acupuncturist with over two decades of clinical practice, who has emerged as a leader in mental health treatment, particularly in the field of depression. A graduate of Robert Wood Johnson Medical School, Dr. Boguslavsky is board-certified in both Family Medicine and Medical Acupuncture, showcasing his diverse medical expertise. His extensive experience spans a wide range of medical care, from acute illnesses to chronic condition management, with a particular focus on preventative care and pain treatment.

Notably, Dr. Boguslavsky has pioneered innovative approaches to depression treatment, having administered over 10,000 Spravato treatments, establishing himself as one of the foremost experts in this cutting-edge therapy. His unique blend of traditional Western medicine, Eastern acupuncture techniques, and advanced psychiatric treatments allows him to offer comprehensive, personalized care to his patients at PremierMD and Spravato Treatment Centers of NJ. Fluent in English and Russian, Dr. Boguslavsky brings a multifaceted approach to healthcare, combining the latest medical technologies with time-honored principles of doctor-patient relationships to address both physical and mental health needs.

Treating Depression with Spravato

While Ketamine is a successful option for 70% of treatment-resistant patients, lack of accessibility, trypanophobia (the fear of needles in a medical setting) and other speedbumps have kept many patients from venturing down the road to Ketamine IV Therapy. Ketamine Infusions have seen great success over the past few years, making it inevitable that a more easily deliverable alternative would be the next step in treating Major Depressive Disorder (MDD.)

Enter Spravato Nasal Spray.

In 2019, the FDA approved Esketamine Spravato™ Nasal Spray as another variation of the Ketamine molecule that could also be effective for treating depression. Spravato is a prescription nasal spray of Esketamine, used for treatment-resistant depression (TRD) or Major Depressive Disorder (MDD) with suicidal thoughts. Spravato contains S-ketamine, a different variation from the Ketamine molecule used in Ketamine IV Therapy.

According to Johns Hopkins Medicine, “Esketamine works in a similar fashion, [as conventional antidepressants] but unlike other antidepressants, it increases levels of glutamate, the most abundant chemical messenger in the brain.”

While conventional antidepressants are more gradual and slow-acting, Esketamine works rapidly and reduces depressive symptoms within a few hours. 33% of people with depression don’t respond to conventional antidepressants, but Esketamine has been known to reduce symptoms in the majority of these clinical trials.

Woman just out of her Spravato depression session in New Jersey
Relief from depression can be yours, too!

Esketamine vs Ketamine

The Ketamine molecule used in Ketamine IV Therapy is racemic, a combination of the R-Ketamine and S-Ketamine molecule, whereas Esketamine is solely comprised of S-Ketamine, making it unique. There are also a number of other factors that differentiate Ketamine and the Esketamine in Spravato, including the method of delivery, bioavailability and dosage amounts.

Unlike traditional Ketamine Treatments, which are administered via IV, Spravato is self-administered in two to three intranasal doses administered in five-minute increments. Spravato is a professional, medical alternative for patients who would prefer to avoid an IV injection. Critically, Spravato is covered by most major insurances, in contrast to IV ketamine treatments.

For more information on Spravato treatments from Spravato Treatment Centers of NJ, visit our Spravato Frequently Asked Questions page

 

Author's Message

David Boguslavsky, MD is an experienced and dedicated family physician with an interest in mental health who has been practicing medicine for almost 2 decades. 

If you are suffering from Major Depression, and have failed to see your depression lift despite 2 antidepressants tried, Spravato therapy maybe right for you. This, insurance-covered, ketamine therapy for depression has helped thousands of patients just like you. To learn more about the costs of Spravato, esketamine’s effectiveness, potential side effects, or to simply take the next step towards feeling better, please reach out to us, we would love to help!

Author’s Bio

Dr. David Boguslavsky, MD, is a highly experienced family physician and medical acupuncturist with over two decades of clinical practice, who has emerged as a leader in mental health treatment, particularly in the field of depression. A graduate of Robert Wood Johnson Medical School, Dr. Boguslavsky is board-certified in both Family Medicine and Medical Acupuncture, showcasing his diverse medical expertise. His extensive experience spans a wide range of medical care, from acute illnesses to chronic condition management, with a particular focus on preventative care and pain treatment.

Notably, Dr. Boguslavsky has pioneered innovative approaches to depression treatment, having administered over 10,000 Spravato treatments, establishing himself as one of the foremost experts in this cutting-edge therapy. His unique blend of traditional Western medicine, Eastern acupuncture techniques, and advanced psychiatric treatments allows him to offer comprehensive, personalized care to his patients at PremierMD and Spravato Treatment Centers of NJ. Fluent in English and Russian, Dr. Boguslavsky brings a multifaceted approach to healthcare, combining the latest medical technologies with time-honored principles of doctor-patient relationships to address both physical and mental health needs.

Esketamine Depression treatment options in New Jersey

Depression is a treatable medical condition that affects millions of people across the world. It’s estimated that some 18% of Americans suffer from depression at some point in their lives, and it affects persons of all ages and backgrounds. 

At Spravato Treatment Centers NJ, we offer state-of-the-art depression treatment solutions. With our background in family Medicine, and our focus on treating the whole individual, we are so much more than your average ketamine infusion center. Critically, our staff is expert at getting this revolutionary treatment for depression, esketamine, to be covered by health insurance.

when depression affects in NJ, spravato treatments can lift depression's veil
Someone depressed can feel so deeply alone

Spravato Treatment for Depression

Spravato is a new treatment for depression that has gained popularity in the mental health community. It works by targeting the neurotransmitters serotonin and norepinephrine to increase their levels in the brain, thus producing a feeling of euphoria and alleviating depression symptoms. In order to be treated with Spravato, you must be referred by your primary care doctor or psychiatrist to an approved clinic that can administer this treatment. The cost of Spravato varies depending on where you live, but it typically costs around $20 per treatment (treated once or twice a week for most patients).

Spravato has been found to be both safe and effective as an antidepressant medication; however, like any other medication it may have side effects such as nausea or vomiting which will lessen over time with continued use as your body adjusts itself to having higher levels of these chemicals circulating through its system

 

 

Woman just out of her Spravato depression session in New Jersey
Relief from depression can be yours, too!

Spravato treatment centers

If you suffer from major depressive disorder, ketamine therapy is a great option to consider. If you’re interested in learning more about how ketamine therapy can help treat your symptoms of depression, contact us today! 

Even if you choose a different Spravato Treatment Center, it is crucial that your designated treatment center is adept in getting your esketamine treatment for depression covered by health insurance

You can find a qualified Spravato Treatment center using a handy tool from Janssen.

Author's Message

David Boguslavsky, MD is an experienced and dedicated family physician with an interest in mental health who has been practicing medicine for almost 2 decades. 

If you are suffering from Major Depression, and have failed to see your depression lift despite 2 antidepressants tried, Spravato therapy maybe right for you. This, insurance-covered, ketamine therapy for depression has helped thousands of patients just like you. To learn more about the costs of Spravato, esketamine’s effectiveness, potential side effects, or to simply take the next step towards feeling better, please reach out to us, we would love to help!

Author’s Bio

Dr. David Boguslavsky, MD, is a highly experienced family physician and medical acupuncturist with over two decades of clinical practice, who has emerged as a leader in mental health treatment, particularly in the field of depression. A graduate of Robert Wood Johnson Medical School, Dr. Boguslavsky is board-certified in both Family Medicine and Medical Acupuncture, showcasing his diverse medical expertise. His extensive experience spans a wide range of medical care, from acute illnesses to chronic condition management, with a particular focus on preventative care and pain treatment.

Notably, Dr. Boguslavsky has pioneered innovative approaches to depression treatment, having administered over 10,000 Spravato treatments, establishing himself as one of the foremost experts in this cutting-edge therapy. His unique blend of traditional Western medicine, Eastern acupuncture techniques, and advanced psychiatric treatments allows him to offer comprehensive, personalized care to his patients at PremierMD and Spravato Treatment Centers of NJ. Fluent in English and Russian, Dr. Boguslavsky brings a multifaceted approach to healthcare, combining the latest medical technologies with time-honored principles of doctor-patient relationships to address both physical and mental health needs.

Depression casts a long shadow over normal life….

Depression is a treatable medical condition that affects millions of people across the world. It’s estimated that some 18% of Americans suffer from depression at some point in their lives, and it affects persons of all ages and backgrounds. 

At Spravato Treatment Centers NJ, we offer state-of-the-art depression treatment solutions. With our background in family Medicine, and our focus on treating the whole individual, we are so much more than your average ketamine infusion center. Critically, our staff is expert at getting this revolutionary treatment for depression, esketamine, to be covered by health insurance.

when depression affects in NJ, spravato treatments can lift depression's veil
Someone depressed can feel so deeply alone

Spravato Treatment for Depression

Spravato is a new treatment for depression that has gained popularity in the mental health community. It works by targeting the neurotransmitters serotonin and norepinephrine to increase their levels in the brain, thus producing a feeling of euphoria and alleviating depression symptoms. In order to be treated with Spravato, you must be referred by your primary care doctor or psychiatrist to an approved clinic that can administer this treatment. The cost of Spravato varies depending on where you live, but it typically costs around $20 per treatment (treated once or twice a week for most patients).

Spravato has been found to be both safe and effective as an antidepressant medication; however, like any other medication it may have side effects such as nausea or vomiting which will lessen over time with continued use as your body adjusts itself to having higher levels of these chemicals circulating through its system

 

 

Woman just out of her Spravato depression session in New Jersey
Relief from depression can be yours, too!

Spravato treatment centers

If you suffer from major depressive disorder, ketamine therapy is a great option to consider. If you’re interested in learning more about how ketamine therapy can help treat your symptoms of depression, contact us today! 

Even if you choose a different Spravato Treatment Center, it is crucial that your designated treatment center is adept in getting your esketamine treatment for depression covered by health insurance

You can find a qualified Spravato Treatment center using a handy tool from Janssen.

Author's Message

David Boguslavsky, MD is an experienced and dedicated family physician with an interest in mental health who has been practicing medicine for almost 2 decades. 

If you are suffering from Major Depression, and have failed to see your depression lift despite 2 antidepressants tried, Spravato therapy may be right for you. This, insurance-covered, ketamine therapy for depression has helped thousands of patients just like you. To learn more about the costs of Spravato, esketamine’s effectiveness, potential side effects, or to simply take the next step towards feeling better, please reach out to us, we would love to help!

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Author’s Bio

Dr. David Boguslavsky, MD, is a highly experienced family physician and medical acupuncturist with over two decades of clinical practice, who has emerged as a leader in mental health treatment, particularly in the field of depression. A graduate of Robert Wood Johnson Medical School, Dr. Boguslavsky is board-certified in both Family Medicine and Medical Acupuncture, showcasing his diverse medical expertise. His extensive experience spans a wide range of medical care, from acute illnesses to chronic condition management, with a particular focus on preventative care and pain treatment.

Notably, Dr. Boguslavsky has pioneered innovative approaches to depression treatment, having administered over 10,000 Spravato treatments, establishing himself as one of the foremost experts in this cutting-edge therapy. His unique blend of traditional Western medicine, Eastern acupuncture techniques, and advanced psychiatric treatments allows him to offer comprehensive, personalized care to his patients at PremierMD and Spravato Treatment Centers of NJ. Fluent in English and Russian, Dr. Boguslavsky brings a multifaceted approach to healthcare, combining the latest medical technologies with time-honored principles of doctor-patient relationships to address both physical and mental health needs.

Spravato for depression

Spravato® is a prescription medication used to treat major depressive disorder (MDD). The active ingredient in Spravato is esketamine, which is a type of medicine called an antidepressant. Esketamine works by acting on the brain chemicals that help maintain mental health. By changing how these chemicals work, esketamine may provide relief from symptoms of depression

Life is often hard for a depressed person

What is Major Depressive Disorder?

Major depressive disorder, or MDD, is a mental health condition that causes a person to feel extremely sad, hopeless, and disinterested in life. Individuals with MDD may also experience physical symptoms such as headaches or exhaustion.

MDD can last for several months or longer. People who have MDD may not be able to function normally at work or school because of their extreme sadness and other symptoms associated with depression.

Now happy person who is working on the computer. He did better on Spravato.

Ketamine therapy for Major Depressive Disorder (MDD)

Ketamine is a powerful and fast-acting antidepressant that has been used to treat depression in people who have not responded to other treatments. This can include those with chronic depression, treatment resistance, or suicidal ideation. It works by blocking the NMDA receptor and causing a release of neurotransmitters in the brain such as serotonin, norepinephrine and dopamine.

Esketamine is an effective treatment for major depression when given intranasally in a safe, comfortable environment. It can take 60 minutes or more before its effects are felt, but some patients notice improvement within 10 minutes of administration. The most common side effects include dizziness, nausea/vomiting, dissociation (feeling unconnected from reality), confusion/disorientation and headache/pain at the injection site; these symptoms should last only one hour after administration ends. When Spravato is administered, the side effects described above are fairly rare, with most patients reporting feeling relaxed and refreshed by the end of their treatments. Some report Spravato sessions to be almost euphoric in the way they lift the depression blanket off the patient. 

Author's Message

David Boguslavsky, MD is an experienced and dedicated family physician with an interest in mental health who has been practicing medicine for almost 2 decades. 

If you are suffering from Major Depression, and have failed to see your depression lift despite 2 antidepressants tried, Spravato therapy maybe right for you. This, insurance-covered, ketamine therapy for depression has helped thousands of patients just like you. To learn more about the costs of Spravato, esketamine’s effectiveness, potential side effects, or to simply take the next step towards feeling better, please reach out to us, we would love to help!

Author’s Bio

Dr. David Boguslavsky, MD, is a highly experienced family physician and medical acupuncturist with over two decades of clinical practice, who has emerged as a leader in mental health treatment, particularly in the field of depression. A graduate of Robert Wood Johnson Medical School, Dr. Boguslavsky is board-certified in both Family Medicine and Medical Acupuncture, showcasing his diverse medical expertise. His extensive experience spans a wide range of medical care, from acute illnesses to chronic condition management, with a particular focus on preventative care and pain treatment.

Notably, Dr. Boguslavsky has pioneered innovative approaches to depression treatment, having administered over 10,000 Spravato treatments, establishing himself as one of the foremost experts in this cutting-edge therapy. His unique blend of traditional Western medicine, Eastern acupuncture techniques, and advanced psychiatric treatments allows him to offer comprehensive, personalized care to his patients at PremierMD and Spravato Treatment Centers of NJ. Fluent in English and Russian, Dr. Boguslavsky brings a multifaceted approach to healthcare, combining the latest medical technologies with time-honored principles of doctor-patient relationships to address both physical and mental health needs.

Depression is common.

Depression is a serious medical condition that affects millions of adults in the United States. According to the National Institute of Mental Health, approximately 16.1 million American adults suffer from depression. That’s a staggering 6.7% of the population!

Depression can cause a lot of different symptoms, including feeling sad, angry, or hopeless; losing interest in activities that you used to enjoy; having trouble sleeping or eating; or feeling tired all the time. Depression can also lead to physical problems, such as headaches or stomach aches. 

While depression is common, it is also treatable. In fact, there have been major advancements in the treatment of depression in recent years. One of the most promising new treatments is ketamine therapy.

Unlike traditional medications for depression, which can take weeks or even months to work, ketamine therapy can provide relief within hours. Spravato/esketamine is covered by most insurance plans, including Aetna, Horizon, United, Cigna and Medicare.

Spravato Treatment Centers of New Jersey work with patients covered by various insurances to make this revolutionary depression therapy available to all NJ patients. In our future posts, we’ll cover what the typical experience would be like for a patient choosing Spravato / esketamine therapy to address their treatment-resistant Major Depression!

Author’s Bio

Dr. David Boguslavsky, MD, is a highly experienced family physician and medical acupuncturist with over two decades of clinical practice, who has emerged as a leader in mental health treatment, particularly in the field of depression. A graduate of Robert Wood Johnson Medical School, Dr. Boguslavsky is board-certified in both Family Medicine and Medical Acupuncture, showcasing his diverse medical expertise. His extensive experience spans a wide range of medical care, from acute illnesses to chronic condition management, with a particular focus on preventative care and pain treatment.

Notably, Dr. Boguslavsky has pioneered innovative approaches to depression treatment, having administered over 10,000 Spravato treatments, establishing himself as one of the foremost experts in this cutting-edge therapy. His unique blend of traditional Western medicine, Eastern acupuncture techniques, and advanced psychiatric treatments allows him to offer comprehensive, personalized care to his patients at PremierMD and Spravato Treatment Centers of NJ. Fluent in English and Russian, Dr. Boguslavsky brings a multifaceted approach to healthcare, combining the latest medical technologies with time-honored principles of doctor-patient relationships to address both physical and mental health needs.